Mass spectrometry enables the discovery of inhibitors of an LPS transport assembly via disruption of protein–protein interactions

3401 Analytical Chemistry

34 Chemical Sciences

Biotechnology

Emerging Infectious Diseases

Biodefense

Infectious Diseases

5.1 Pharmaceuticals

Anti-Infective Agents

Crystallization

High-Throughput Screening Assays

Humans

Lipopolysaccharide Receptors

Mass Spectrometry

Oxazines

Peptides

Protein Binding

Protein Multimerization

Quinolines

Small Molecule Libraries

Structure-Activity Relationship