Prevalence and clinical burden of NDM-1 positive infections in pediatric and neonatal patients in Pakistan.

Qamar MU, Nahid F, Walsh TR, Kamran R, Zahra R

In a neonatal/pediatric Gram-negative infection study from Islamabad, 71/82 strains were carbapenem resistant with 12/82 positive for New Delhi Metallo-β-lactamase and many being extensively antibiotic resistant. Burden and outcome analysis on 9 patients showed that 4/9 died after inadequate therapy regardless of organism type.

Keywords:

Humans

,

Gram-Negative Bacteria

,

Gram-Negative Bacterial Infections

,

Carbapenems

,

beta-Lactamases

,

Anti-Bacterial Agents

,

Microbial Sensitivity Tests

,

Prevalence

,

Survival Analysis

,

Polymerase Chain Reaction

,

Drug Resistance, Bacterial

,

Child, Preschool

,

Infant

,

Infant, Newborn

,

Pakistan

,

Female

,

Male