Dr Jie Huang
My pronouns are he/him
My main interest focuses on plant-pathogen interaction. 1) The roles of pre-mRNA alternative splicing (AS) in plant - Phytophthora interactions. For example, we describe a functional characterization of the effector PsAvr3c from Phytophthora sojae, which physically binds to and stabilizes soybean splicing factors GmSKRPs and reprogram host pre-mRNA splicing to promote disease (Huang et al., 2017). Besides, we also examined the global AS changes in tomato leaves infected with P. infestans, we show that AS is a distinct layer of transcriptome reprogramming during plant-pathogen interactions. Furthermore, we established a novel AS reporter system to identify nine splicing regulatory effectors (SREs) from P. infestans effectors (Huang et al., 2020). 2) Apoplast manipulation of Solanaceous plants by bacterial microbes. I studied the dynamics of secreted plant hydrolases during infection using activity-based proteomics.