Jun Fang

Research Interests

My pronouns are she/her.

My major research topic in Jarvis lab is to carry out advanced biochemical analysis to address the mechanistic details of SP1, SP2, and CDC48 in the CHLORAD system. To do this, I am purifying proteins from bacteria and plants, and reconstituting the purified proteins and plant lipids into proteoliposomes for in vitro reconstitution assays. My research during my PhD has focused on characterizing the function of an Arabidopsis chloroplast outer membrane protein, Crumpled Leaf (CRL), under the supervision of Prof Chanhong Kim in Shanghai Center for Plant Stress Biology (PSC), CAS Center for Excellence in Molecular Plant Sciences (CEMPS), Chinese Academy of Sciences (CAS), China. The loss of the CRL protein leads to a severe plastid division defect, abnormal cell cycle, constitutively upregulated stress-responsive genes, and spontaneous autoimmune response. We combined structural biology, plant genetics, plant biochemistry, cell biology, and analytical chemistry to investigate the function of CRL.